Bromelain Information | Ingredient Guide
found in the stem and juice of the pineapple, bromelain is primarily extracted
from stems after the fruit of the pineapple is used for other purposes. In Taiwan, India and Thailand,
producers of bromelain supplements peel, crush and then press pineapple stems
to obtain soluble bromelain enzymes that are later purified and concentrated.
In addition to being used as a meat tenderizer, bromelain
may have strong anti-inflammatory properties as well as the ability to inhibit
tumor cell growth and delay the formation of blood clots in cardiovascular
The U.S. National Institute of Health states
that bromelain may be effective for relieving the pain and inflammation of
osteoarthritis when bromelain is taken as Phlogenzym,
a medication containing bromelain and other proteins.
Some people take bromelain to prevent muscle fatigue following vigorous
exercise but as yet, no clinical evidence exists for the efficacy of bromelain
as a post-workout aid.
How Does Bromelain Affect the Body?
synthesis of prostaglandin (hormone-like lipids that regulate pathogenic
mechanisms responsible for inflammatory responses), bromelain is able to
provide its documented inflammatory effects. In addition, bromelain extract increases
fibrinolytic activity in the bloodstream that can expedite wound healing by
degrading fibrin, a substance which inhibits blood clotting in open wounds.
Some studies found that bromelain reduces release of proinflammatory
cytokines and chemokines that are thought to be the mechanistic chemicals
behind Crohn's disease, ulcerative colitis and inflammatory bowel disease.
Potential Health Benefits of
As an potential anti-inflammatory, bromelain may be used to reduce swelling
and inflammation following minimally invasive surgeries involving moist tissues
(nose/sinus/oral operations, for example). The
American Cancer Society reports that a few studies indicated that bromelain
may also help decrease side effects of chemotherapy, such as nausea and
Bromelain may also reduce allergy and asthma symptoms in addition to the
pain and stiffness of tendonitis, joint pain, ACL tears and sprains.
Effects of Bromelain
Intestinal discomfort and diarrhea are the only side effects
that have been reported by people using bromelain extract supplements. However,
not enough is known about bromelain to make it safe for use by pregnant or
breast-feeding women. Those with
Bromelain is known to interact with amoxicillin by
increasing concentrations of this antibiotic in the body. Additionally, taking
bromelain with other antibiotics like tetracycline may increase side effects
caused by these drugs. Blood clotting preventatives such as Plavix and aspirin
could also be inhibited by bromelain and induce bleeding and bruising.
Usual dosage suggestions when taking bromelain supplements
is between 250 and 500 milligrams daily, depending on how much is needed to
reduce existing inflammatory conditions.