MTS Tyrant: Control Cortisol, Regulate Estrogen
New MTS Nutrition Tyrant is a revolutionary supplement designed to control cortisol, regulate estrogen, and improve your overall health. Cortisol is a steroid hormone naturally produced by the human body in the adrenal gland. Cortisol is produced and released during stressful situations. It affects bone growth, blood pressure, immune system, and nervous system function. [1]
Prolonged periods of high cortisol levels can cause fatigue, lead to fat gain, and negatively affect sleep. Estrogen is the sex steroid hormone comprised of Estradiol, Estriol, and Estrone. it's produced in the highest concentrations in the female ovaries but is also naturally produced in the liver, adrenal glands, breasts, and male testes. Elevated estrogen levels may increase fat storage and risk of developing prostate and/or pancreatic cancers. [2]
Numerous health consequences accompany exceptionally high or low cortisol and estrogen levels. it's important to keep both cortisol and estrogen within the normal and acceptable range, naturally if possible.
MTS Tyrant is an all-natural supplement that never needs to be cycled, requires just one dosage per day, and has over 1,000mg of active ingredients per serving. To maximize the effects of MTS Tyrant you should consume 1 serving (2 capsules) with the last meal of the day. it's comprised of 4 clinically-studied ingredients at clinically effective doses in a non-proprietary blend - Phosphatidylserine (500mg), Green Tea Extract (500mg), Diindolylmethane (250mg), and Calcium d-Glucarate (250mg).
Phosphatidylserine, also known as PS, is an amino-acid derived phospholipid comprising the majority of the inner cell membrane. it's produced by the human body in small quantities but is predominantly obtained through food.
it's most commonly isolated from cows, cabbage, or soy. At a high level phosphatidylserine improves brain function and controls cortisol levels. The Mayo Clinic confirmed that phosphatidylserine can improve cognitive abilities and behaviors, making it an excellent compound for those looking to improve their memory and those with degenerative memory issues such as Alzheimer's disease. [3] Daily oral doses of 100mg to 500mg are ideal for those looking to improve cognitive function as measured via memory recognition, memory recall, executive functions, mental flexibility, total learning and immediate recall. [4][5]
Phosphatidylserine is considered a nootropic due to its positive effects on the brain. Phosphatidylserine also regulates the release of key neurotransmitters - acetylcholine, dopamine, and noradrenaline. [4] During a 10-day study of 9 healthy males 800mg/day of this compound reduced the cortisol response and adrenocorticotropic hormone release in response to physical activity without affecting growth hormone or prolactin levels. [6]
Phosphatidylserine will help you recover faster from your workout without slowing muscle and strength growth. A second study found that 750mg/day of phosphatidylserine improves work capacity during high intensity cardiovascular exercise (e.g. cycling and running), making it an excellent compound for those looking to increase overall athletic performance. [4] For those looking to improve mood and decrease feelings of stress, just 300mg/day of this potent compound will suffice.7 300mg/day of this compound over 12 weeks did reduce systolic and diastolic blood pressure in 30 elderly (ages 50-90) volunteers with memory complaints. [5]
Those with issues related to or taking medication for blood pressure should consult with a physician before using this compound. Phosphatidylserine is an excellent natural compound designed to improve athletic performance, control cortisol levels during intense physical exercise, improve your mood, and enhance your memory.
A thrice daily consumption 90mg of EGCG and 50mg of caffeine significantly increased 24-hour energy expenditure by 4% compared to placebo and caffeine-only dosing protocols. [8] Increased energy expenditure can trigger both thermogenesis and fat oxidation, which can help you drop inches off the waist and hips as well as help you lose those last few pounds of stubborn fat. Just 200 to 300mg of EGCG per day can prevent decline in cardiovascular and metabolic health. [9]
Numerous studies support green tea extract as a potent anti-cancer compound and a nootropic capable of increasing both working memory and task performance. [9][10] A meta-analysis of 31 studies found that green tea consumption can significantly decrease the risk of colon, urinary bladder, stomach, esophagus, lung, and pancreatic cancer. [11] Green tea acts by slowing or shutting down cancerous cell enlargement and division. Green tea extract might be one of the healthiest compounds on earth.
DIM accomplishes this by binding to both aryl hydrocarbon receptors and estrogen receptors. [13] One study found that 108mg/day of DIM for 30 days can increase the good to bad estrogen ratio by 47% compared to placebo. [14] Diindolylmethane also increases Interferon-Gamma (IFN-?), indicating that this compound strengthens your immune system. [15]
In addition to estrogen-control and immunoprotective benefits, DIM is also a potent anticancer agent. Diindolylmethane expedites the killing of human tumor and cancerous cells through apoptosis (also known as programmed cell death). [12] In clinical studies DIM inhibited the growth of ovarian, breast, and prostate cancer cells. [16][17]
If you're still not convinced about the efficacy of DIM, consider its safety - immature and adult rats exhibited no adverse effects when dosed with 10x the recommended daily dose (20.0mg/kg/day). [18] Diindolylmethane?s inclusion in the MTS Tyrant formula will encourage your body to naturally produce the right hormones while improving your immune function.
Oral consumption of this compound may also decreases risk for breast, prostate, and colon cancers by inhibiting beta-glucuronidase. [19] Researchers believe calcium d-glucarate has strong anticancer properties. One study found that this compound lowers endogenous levels of estradiol and precursors of 17-ketosteroids which in turn slows or stops the growth of cancerous mammary cells. [21]
Clinical evidence also suggests calcium d-glucarate can be used to regulate estrogen metabolism and lower-lipids (e.g. cholesterol, triglycerides, and other fatty acids). [19] When the dosing is extrapolated for human subjects, a daily dose of 200-1,000mg/kg of bodyweight appears to be effective. [20] Calcium d-Glucarate is an excellent compound for increasing the body?s elimination of cancer-promoting toxins and estrogens.
2) Broeder, C. E. "Oral Andro-related Prohormone Supplementation: Do the Potential Risks Outweigh the Benefits?" National Center for Biotechnology Information. Can J Appl Physiol, Feb. 2003.
3) Smith, Glenn. "Phosphatidylserine Supplements: Can They Improve Memory?" Mayo Clinic. Mayo Foundation for Medical Education and Research, 2015.
4) Kingsley, M. "Effects of Phosphatidylserine Supplementation on Exercising Humans." National Center for Biotechnology Information. Sports Med., 2006.
5) Richter, Y., et al. "The Effect of Soybean-derived Phosphatidylserine on Cognitive Performance in Elderly with Subjective Memory Complaints: a Pilot Study." National Center for Biotechnology Information. Clin Interv Aging., 2013.
6) Monteleone, P. "Blunting by Chronic Phosphatidylserine Administration of the Stress-induced Activation of the Hypothalamo-pituitary-adrenal Axis in Healthy Men." National Center for Biotechnology Information. Eur J Clin Pharmacol., 1992.
7) Benton, D., et al. "The Influence of Phosphatidylserine Supplementation on Mood and Heart Rate when Faced with an Acute Stressor." National Center for Biotechnology Information. Nutr Neurosci., 2001.
8) Dulloo, A. G. "Efficacy of a Green Tea Extract Rich in Catechin Polyphenols and Caffeine in Increasing 24-h Energy Expenditure and Fat Oxidation in Humans." National Center for Biotechnology Information. Am J Clin Nutr., Dec. 1999.
9) Wolfram, S. "Effects of Green Tea and EGCG on Cardiovascular and Metabolic Health." National Center for Biotechnology Information. J Am Coll Nutr., Aug. 2007.
10) Schmidt, A., et al. "Green Tea Extract Enhances Parieto-frontal Connectivity During Working Memory Processing." National Center for Biotechnology Information. Psychopharmacology (Berl), Oct. 2014.
11) Janle, Elsa M. et al. ?Pharmacokinetics of Green Tea Catechins in Extract and Sustained-Release Preparations.? Journal of dietary supplements 5.3 (2008): 248?263. PMC.
12) "Diindolylmethane." National Cancer Institute Drug Dictionary. National Institutes of Health, 2015.
13) Mulvey, Laura et al. ?Interplay of Genes Regulated by Estrogen and Diindolylmethane in Breast Cancer Cell Lines.? Molecular Medicine 13.1-2 (2007): 69?78. PMC.
14) Dalessandri, K. M. "Pilot Study: Effect of 3,3'-diindolylmethane Supplements on Urinary Hormone Metabolites in Postmenopausal Women with a History of Early-stage Breas..." National Center for Biotechnology Information. Nutr Cancer, 2004.
15) Sepkovic, Daniel W. et al. ?Diindolylmethane Inhibits Cervical Dysplasia, Alters Estrogen Metabolism and Enhances Immune Response in The K14-HPV16 Transgenic Mouse Model.? Cancer epidemiology, biomarkers & prevention?: a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 18.11 (2009): 2957?2964. PMC.
16) Kandala, Prabodh K, and Sanjay K Srivastava. ?Diindolylmethane Suppresses Ovarian Cancer Growth and Potentiates the Effect of Cisplatin in Tumor Mouse Model by Targeting Signal Transducer and Activator of Transcription 3 (STAT3).? BMC Medicine 10 (2012): 9. PMC.
17) Vivar, Omar I. et al. ?Selective Activation of Estrogen Receptor-? Target Genes by 3,3?-Diindolylmethane.? Endocrinology 151.4 (2010): 1662?1667. PMC.
18) Elackattu, Alphi P., Lining Feng, and Zhi Wang. ?A CONTROLLED SAFETY STUDY OF DIINDOLYLMETHANE IN THE IMMATURE RAT MODEL.? The Laryngoscope 119.9 (2009): 1803?1808. PMC.
19) "Calcium-D-glucarate." National Center for Biotechnology Information. Altern Med Rev, Aug. 2002.
20) Orwell, Sol, and Kurtis Frank. "Calcium-D-Glucarate." Examine.com. N.p., 2015.
21) Walaszek, Z., et al. "Dietary Glucarate As Anti-promoter of 7,12-dimethylbenz[a]anthracene-induced Mammary Tumorigenesis." National Center for Biotechnology Information. Carcinogenesis, Sept. 1986.
Prolonged periods of high cortisol levels can cause fatigue, lead to fat gain, and negatively affect sleep. Estrogen is the sex steroid hormone comprised of Estradiol, Estriol, and Estrone. it's produced in the highest concentrations in the female ovaries but is also naturally produced in the liver, adrenal glands, breasts, and male testes. Elevated estrogen levels may increase fat storage and risk of developing prostate and/or pancreatic cancers. [2]
Numerous health consequences accompany exceptionally high or low cortisol and estrogen levels. it's important to keep both cortisol and estrogen within the normal and acceptable range, naturally if possible.
MTS Tyrant is an all-natural supplement that never needs to be cycled, requires just one dosage per day, and has over 1,000mg of active ingredients per serving. To maximize the effects of MTS Tyrant you should consume 1 serving (2 capsules) with the last meal of the day. it's comprised of 4 clinically-studied ingredients at clinically effective doses in a non-proprietary blend - Phosphatidylserine (500mg), Green Tea Extract (500mg), Diindolylmethane (250mg), and Calcium d-Glucarate (250mg).
MTS Tyrant Ingredients
Phosphatidylserine (500mg)
Phosphatidylserine, also known as PS, is an amino-acid derived phospholipid comprising the majority of the inner cell membrane. it's produced by the human body in small quantities but is predominantly obtained through food.it's most commonly isolated from cows, cabbage, or soy. At a high level phosphatidylserine improves brain function and controls cortisol levels. The Mayo Clinic confirmed that phosphatidylserine can improve cognitive abilities and behaviors, making it an excellent compound for those looking to improve their memory and those with degenerative memory issues such as Alzheimer's disease. [3] Daily oral doses of 100mg to 500mg are ideal for those looking to improve cognitive function as measured via memory recognition, memory recall, executive functions, mental flexibility, total learning and immediate recall. [4][5]
Phosphatidylserine is considered a nootropic due to its positive effects on the brain. Phosphatidylserine also regulates the release of key neurotransmitters - acetylcholine, dopamine, and noradrenaline. [4] During a 10-day study of 9 healthy males 800mg/day of this compound reduced the cortisol response and adrenocorticotropic hormone release in response to physical activity without affecting growth hormone or prolactin levels. [6]
Phosphatidylserine will help you recover faster from your workout without slowing muscle and strength growth. A second study found that 750mg/day of phosphatidylserine improves work capacity during high intensity cardiovascular exercise (e.g. cycling and running), making it an excellent compound for those looking to increase overall athletic performance. [4] For those looking to improve mood and decrease feelings of stress, just 300mg/day of this potent compound will suffice.7 300mg/day of this compound over 12 weeks did reduce systolic and diastolic blood pressure in 30 elderly (ages 50-90) volunteers with memory complaints. [5]
Those with issues related to or taking medication for blood pressure should consult with a physician before using this compound. Phosphatidylserine is an excellent natural compound designed to improve athletic performance, control cortisol levels during intense physical exercise, improve your mood, and enhance your memory.
Green Tea Extract (500mg)
The green tea leaf has been used for thousands of years to improve overall health and promote fat loss. Instead of having to drink gallons of green tea per day to experience the benefits of this wonder plant MTS Tyrant utilizes the green tea leaves/arial parts to create an extract comprised of 50% Epigallocatechin gallate (EGCG)/95% Polyphenols.A thrice daily consumption 90mg of EGCG and 50mg of caffeine significantly increased 24-hour energy expenditure by 4% compared to placebo and caffeine-only dosing protocols. [8] Increased energy expenditure can trigger both thermogenesis and fat oxidation, which can help you drop inches off the waist and hips as well as help you lose those last few pounds of stubborn fat. Just 200 to 300mg of EGCG per day can prevent decline in cardiovascular and metabolic health. [9]
Numerous studies support green tea extract as a potent anti-cancer compound and a nootropic capable of increasing both working memory and task performance. [9][10] A meta-analysis of 31 studies found that green tea consumption can significantly decrease the risk of colon, urinary bladder, stomach, esophagus, lung, and pancreatic cancer. [11] Green tea acts by slowing or shutting down cancerous cell enlargement and division. Green tea extract might be one of the healthiest compounds on earth.
MTS Nutrition CEO Marc "The Machine" Lobliner discusses his latest product; Tyrant.
Diindolylmethane (250mg)
Diindolylmethane, also known as DIM or 3,3?-Diindolylmethane, is a phytonutrient compound naturally found in cruciferous vegetables like broccoli, cauliflower, cabbage, and brussels sprouts. DIM shifts and regulates estrogen metabolism in both males and females by decreasing the amount of 16-hydroxy estrogen metabolites (bad estrogen) and increasing the amount of 2-hydroxy estrogen metabolites (good estrogen). [12]DIM accomplishes this by binding to both aryl hydrocarbon receptors and estrogen receptors. [13] One study found that 108mg/day of DIM for 30 days can increase the good to bad estrogen ratio by 47% compared to placebo. [14] Diindolylmethane also increases Interferon-Gamma (IFN-?), indicating that this compound strengthens your immune system. [15]
In addition to estrogen-control and immunoprotective benefits, DIM is also a potent anticancer agent. Diindolylmethane expedites the killing of human tumor and cancerous cells through apoptosis (also known as programmed cell death). [12] In clinical studies DIM inhibited the growth of ovarian, breast, and prostate cancer cells. [16][17]
If you're still not convinced about the efficacy of DIM, consider its safety - immature and adult rats exhibited no adverse effects when dosed with 10x the recommended daily dose (20.0mg/kg/day). [18] Diindolylmethane?s inclusion in the MTS Tyrant formula will encourage your body to naturally produce the right hormones while improving your immune function.
Calcium d-Glucarate (250mg)
Calcium d-Glucarate is the calcium salt of D-glucaric acid, a sugar acid derived from D-glucose, that is naturally produced by the human body in small quantities is predominantly obtain through fruits and vegetables. [19] The highest concentrations of this compound, in descending order, is found in peeled oranges, carrots, spinach, apples, broccoli, alfalfa sprouts, and peeled potatoes. [20] Calcium d-Glucarate can suppress tumor growth by more than 70%. [21]Oral consumption of this compound may also decreases risk for breast, prostate, and colon cancers by inhibiting beta-glucuronidase. [19] Researchers believe calcium d-glucarate has strong anticancer properties. One study found that this compound lowers endogenous levels of estradiol and precursors of 17-ketosteroids which in turn slows or stops the growth of cancerous mammary cells. [21]
Clinical evidence also suggests calcium d-glucarate can be used to regulate estrogen metabolism and lower-lipids (e.g. cholesterol, triglycerides, and other fatty acids). [19] When the dosing is extrapolated for human subjects, a daily dose of 200-1,000mg/kg of bodyweight appears to be effective. [20] Calcium d-Glucarate is an excellent compound for increasing the body?s elimination of cancer-promoting toxins and estrogens.
Conclusion
MTS Tyrant provide 1,000mg of active ingredients proven to control cortisol, regulate estrogen, and maximize your overall health. For a little over $1.00 per day you'll receive clinically effective doses of Phosphatidylserine, Green Tea Extract, Diindolylmethane, and Calcium d-Glucarate.
Requiring just one daily dosage of 2 capsules per day this product packs a powerful punch. you'll never have to worry about cycling off of or failing a drug test due to MTS Tyrant as this product is comprised of all-natural WADA-approved ingredients.
Stack MTS Tyrant with MTS Drop Factor and Yohimbine HCL to incinerate fat, suppress your appetite, and preserve your lean mass. When it comes maximizing your athletic performance and general health, MTS Nutrition knows - It's Not a Game!
References
1) Wisse, Brent. "Cortisol Blood Test." MedlinePlus Medical Encyclopedia. U.S. National Library of Medicine, 2013.2) Broeder, C. E. "Oral Andro-related Prohormone Supplementation: Do the Potential Risks Outweigh the Benefits?" National Center for Biotechnology Information. Can J Appl Physiol, Feb. 2003.
3) Smith, Glenn. "Phosphatidylserine Supplements: Can They Improve Memory?" Mayo Clinic. Mayo Foundation for Medical Education and Research, 2015.
4) Kingsley, M. "Effects of Phosphatidylserine Supplementation on Exercising Humans." National Center for Biotechnology Information. Sports Med., 2006.
5) Richter, Y., et al. "The Effect of Soybean-derived Phosphatidylserine on Cognitive Performance in Elderly with Subjective Memory Complaints: a Pilot Study." National Center for Biotechnology Information. Clin Interv Aging., 2013.
6) Monteleone, P. "Blunting by Chronic Phosphatidylserine Administration of the Stress-induced Activation of the Hypothalamo-pituitary-adrenal Axis in Healthy Men." National Center for Biotechnology Information. Eur J Clin Pharmacol., 1992.
7) Benton, D., et al. "The Influence of Phosphatidylserine Supplementation on Mood and Heart Rate when Faced with an Acute Stressor." National Center for Biotechnology Information. Nutr Neurosci., 2001.
8) Dulloo, A. G. "Efficacy of a Green Tea Extract Rich in Catechin Polyphenols and Caffeine in Increasing 24-h Energy Expenditure and Fat Oxidation in Humans." National Center for Biotechnology Information. Am J Clin Nutr., Dec. 1999.
9) Wolfram, S. "Effects of Green Tea and EGCG on Cardiovascular and Metabolic Health." National Center for Biotechnology Information. J Am Coll Nutr., Aug. 2007.
10) Schmidt, A., et al. "Green Tea Extract Enhances Parieto-frontal Connectivity During Working Memory Processing." National Center for Biotechnology Information. Psychopharmacology (Berl), Oct. 2014.
11) Janle, Elsa M. et al. ?Pharmacokinetics of Green Tea Catechins in Extract and Sustained-Release Preparations.? Journal of dietary supplements 5.3 (2008): 248?263. PMC.
12) "Diindolylmethane." National Cancer Institute Drug Dictionary. National Institutes of Health, 2015.
13) Mulvey, Laura et al. ?Interplay of Genes Regulated by Estrogen and Diindolylmethane in Breast Cancer Cell Lines.? Molecular Medicine 13.1-2 (2007): 69?78. PMC.
14) Dalessandri, K. M. "Pilot Study: Effect of 3,3'-diindolylmethane Supplements on Urinary Hormone Metabolites in Postmenopausal Women with a History of Early-stage Breas..." National Center for Biotechnology Information. Nutr Cancer, 2004.
15) Sepkovic, Daniel W. et al. ?Diindolylmethane Inhibits Cervical Dysplasia, Alters Estrogen Metabolism and Enhances Immune Response in The K14-HPV16 Transgenic Mouse Model.? Cancer epidemiology, biomarkers & prevention?: a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 18.11 (2009): 2957?2964. PMC.
16) Kandala, Prabodh K, and Sanjay K Srivastava. ?Diindolylmethane Suppresses Ovarian Cancer Growth and Potentiates the Effect of Cisplatin in Tumor Mouse Model by Targeting Signal Transducer and Activator of Transcription 3 (STAT3).? BMC Medicine 10 (2012): 9. PMC.
17) Vivar, Omar I. et al. ?Selective Activation of Estrogen Receptor-? Target Genes by 3,3?-Diindolylmethane.? Endocrinology 151.4 (2010): 1662?1667. PMC.
18) Elackattu, Alphi P., Lining Feng, and Zhi Wang. ?A CONTROLLED SAFETY STUDY OF DIINDOLYLMETHANE IN THE IMMATURE RAT MODEL.? The Laryngoscope 119.9 (2009): 1803?1808. PMC.
19) "Calcium-D-glucarate." National Center for Biotechnology Information. Altern Med Rev, Aug. 2002.
20) Orwell, Sol, and Kurtis Frank. "Calcium-D-Glucarate." Examine.com. N.p., 2015.
21) Walaszek, Z., et al. "Dietary Glucarate As Anti-promoter of 7,12-dimethylbenz[a]anthracene-induced Mammary Tumorigenesis." National Center for Biotechnology Information. Carcinogenesis, Sept. 1986.
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