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USPLabs Compound 20 | On Sale Now at Tiger Fitness Online!
About 20 years ago, the Beta-2 andrenoceptor became legendary virtually overnight when bodybuilders began to notice the incredible effects certain asthma drugs had on developing lean muscle and burning bodyfat...
Bigger, Stronger AND Leaner? Ok, Keep Talking...
In short, this receptor, when activated, can increase cAMP, which activates Akt signaling, which results in decreased muscle catabolism by decreasing expression of various muscle specific ubiquitin protein ligases (e.g., atrogin-1/MAFbx), which are thought to be responsible for muscle protein degradation...
Furthermore, working through cAMP and non-cAMP mediated mechanisms, ultimately results in increased activation of mammalian target of rapamycin (mTOR) signaling...
In a nutshell, it can potentially prevent muscle from breaking down, while also increasing muscle size...
If this weren't enough, by also increasing cAMP in fat tissue, Hormone Sensitive Lipase (HSL) is activated, which stimulates lipolysis and can potentially lead to a reduction of fat mass!
Spillover - Avoid At All Costs!
You see, your body not only has Beta-2 receptors, it also has additional closely-related receptors that most compounds in this class have "spillover" towards - meaning they activate the Beta-2 receptor, but also activate others...
...More is better right? Not in this case...
Related receptors are located on places other than muscle & fat - so that's why some potent Beta-2 agonists come with nasty side effects like extreme jitters, cramping and an overall "feel like crap" day in and day out...
...It's not the Beta-2 activation that causes these issues - it's the spillover...
Super-Selective Beta-2 Activity
Independent third-party research has uncovered compounds that are found in food that are so selective, scientific data shows it almost exclusively activates Beta-2 in vitro...
This lead to the formulation of: Compound 20
A New Category?
Of course, as the results from our beta-testing logs poured in, everyone tried to figure out exactly what "category" Compound 20 was in...
Can't Put This Bad Boy In A Box
Get ready for an entire new category, one that can be used by itself or within your stack (unless your goal is to get fat and weak!)...Category Awesome
Compound 20 Formula Breakdown
N-Coumaroyldopamine & N-caffeoyldopamine
These particular compounds that are found in foods which have been consumed for hundreds of years have been shown to have incredibly potent - and selective - beta 2-adrenoceptor agonist properties in vitro...
In fact, their potency in terms of increasing cAMP is greater than that of salbutamol and rivals that of the clenbuterol, often used to, "harden", the physique by increasing muscle and decreasing fat mass (1).
It is believed to do so by activating the same signaling pathway that the powerful anabolic hormones, insulin and IGF-1, are able to activate...
In short, coumaroyldopamine & caffeoyldopamine have demonstrated the ability in vitro to increase cAMP and in turn activate Akt signaling...
Furthermore, these incredible compounds may also be able to increase muscle mass by cAMP and non-cAMP mediated mechanism (also involving Akt activation) which ultimately result in increased activation of mammalian target of rapamycin (mTOR) signaling (2,3).
Yet, another mechanism is by potentially modifying polyamine levels (androgens and GH are thought to potentially increase muscle hypertrophy by doing this), it can create yet another mechanism enabling muscle growth (5).
So, the compounds are able to activate pathways involved in the inhibition of skeletal muscle atrophy, while also being able to activate pathways involved in skeletal muscle hypertrophy. In short, it can potentially prevent muscle from being broken down, while also increasing muscle size.
But wait, just like an infomercial, that's not all...
If this weren't enough, by also increasing cAMP in fat tissue, Hormone Sensitive Lipase (HSL), which stimulates lipolysis, can be activated and lead to a reduction of fat mass.
Symplocos Racemosa Extract (standardized for triterpenoids)
This very specific extract was designed to maximize the levels of compounds which can have an additive or even synergistic effect with coumaroyldopamine & caffeoyldopamine by further enhancing their cAMP-increasing effects. It does this in part by inhibiting the degradation of cAMP...
It also goes without saying that this in turn enhances the anti-catabolic/anabolic and lipolytic effects of the coumaroyldopamine & caffeoyldopamine.
In addition, extraction for specific triterpenoid compounds is also expected to further enhance the potential ability of the formulation to increase muscle mass and decrease fat mass by enhancing skeletal muscle insulin/IGF-1 signaling, as was shown with similar compounds in animal models and in vitro (4).
Clinical studies are pending to evaluate Compound 20 and its effects upon body composition.
My Future Unborn Baby Understands How Groundbreaking Compound 20 Truly Is...
Incredible by itself, complete game changer when stacked with thermo's or anabolics...
WARNING: Don't expect to be "stimmed" from Compound 20
When's The Last Time You Looked In The Mirror And Said "I'd Like To Lose My Muscle And Gain Some Fat!"
Umm, that would be never and exactly why you need to get on Compound 20 NOW with its wide variety of stack applications:
Lean Bulk - This is the most obvious as this user is already tailoring his diet, training & supplementation to "gain lean mass & get ripped".
Cutting - Anyone who begins cutting would give just about anything to keep their muscle while shredding up. Imagine being pumped all day on a low carbohydrate diet!
USPLabs Compound 20 Review | Detailed Compound 20 Reviews
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